Preclinical discovery of ixabepilone, a highly active antineoplastic agent
نویسندگان
چکیده
منابع مشابه
Ixabepilone: a novel antineoplastic agent with low susceptibility to multiple tumor resistance mechanisms.
Tumor resistance to chemotherapeutic agents ultimately leads to treatment failure in the majority of cancer patients. The identification of new agents that are less susceptible to mechanisms of tumor resistance could, therefore, bring significant clinical benefits to patients with advanced cancer. One new drug class of great interest in this respect is the epothilones and their analogues, which...
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ژورنال
عنوان ژورنال: Cancer Chemotherapy and Pharmacology
سال: 2008
ISSN: 0344-5704,1432-0843
DOI: 10.1007/s00280-008-0724-8